Industry: Chemical & Material
Published Date: 2026-01-09
Pages: 125 Pages
Report ld: 5638749
Request Sample
Customized Report
The global Dl-3-N-Butylphthalide market was valued at US$ million in 2025 and is anticipated to reach US$ million by 2032, at a CAGR of %from 2026 to 2032.
The 2025 U.S. tariff policies introduce profound uncertainty into the global economic landscape. This report critically examines the implications of recent tariff adjustments and international strategic countermeasures on Dl-3-N-Butylphthalide competitive dynamics, regional economic interdependencies, and supply chain reconfigurations.
DL-3-n-Butylphthalide is the racemic form of (-)-butylphthalide, a phthalide that has been found in A. graveolens, that has diverse biological activities, including antiplatelet, neuroprotective, and antioxidative properties. DL-3-n-Butylphthalide inhibits ADP-, thrombin-, and arachidonic acid-induced aggregation of isolated washed human platelets when used at concentrations of 30, 100, and 300 µM, respectively. It inhibits the phosphorylation of calcium-dependent cytosolic phospholipase A2 (cPLA2) induced by ADP and reduces thromboxane A2 (TXA2) production induced by thrombin or collagen in isolated washed human platelets at concentrations ranging from 30 to 300 µM. DL-3-n-Butylphthalide also inhibits caspase-3 activation, decreases reactive oxygen species (ROS) production and JNK phosphorylation, and prevents cell death induced by serum deprivation in primary mouse cortical neurons when used at a concentration of 10 µM. It reduces infarct volume, as well as caspase-3 activation and JNK phosphorylation in the peri-infarct region, in a mouse model of right middle cerebral artery occlusion (MCAO) with bilateral common carotid artery ligation when administered at a dose of 100 mg/kg one hour following occlusion.
The North American market for Dl-3-N-Butylphthalide is projected to increase from US$ million in 2025 to US$ million by 2032, at a CAGR of % over 2026–2032.
The Asia-Pacific market for Dl-3-N-Butylphthalide is projected to rise from US$ million in 2025 to US$ million by 2032, at a CAGR of % over 2026–2032.
Major global manufacturers of Dl-3-N-Butylphthalide include Xianju Pharmaceutical, CSPC Pharmaceutical, etc. In 2025, the world's top three vendors accounted for approximately % of revenue.
This report delivers a comprehensive overview of the global Dl-3-N-Butylphthalide market, with both quantitative and qualitative analyses, to help readers develop growth strategies, assess the competitive landscape, evaluate their position in the current market, and make informed business decisions regarding Dl-3-N-Butylphthalide. The Dl-3-N-Butylphthalide market size, estimates, and forecasts are provided in terms of shipments (kg) and revenue (US$ millions), with 2025 as the base year and historical and forecast data for 2021–2032.
The report segments the global Dl-3-N-Butylphthalide market comprehensively. Regional market sizes by Type, by Application, , and by company are also provided. For deeper insight, the report profiles the competitive landscape, key competitors, and their respective market rankings, and discusses technological trends and new product developments.
This report will assist Dl-3-N-Butylphthalide manufacturers, new entrants, and companies across the industry value chain with information on revenues, production, and average prices for the overall market and its sub-segments, by company, by Type, by Application, and by region.
MARKET SEGMENTATION
CHAPTER OUTLINE
Chapter 1: Defines the scope of the report and presents an executive summary of market segments (by Type, by Application, , etc.), including the size of each segment and its future growth potential. It offers a high-level view of the current market and its likely evolution in the short, medium, and long term.
Chapter 2: Provides a detailed analysis of the competitive landscape for Dl-3-N-Butylphthalide manufacturers, including prices, production, value-based market shares, latest development plans, and information on mergers and acquisitions.
Chapter 3: Examines Dl-3-N-Butylphthalide production/output and value by region and country, providing a quantitative assessment of market size and growth potential for each region over the next six years.
Chapter 4: Analyzes Dl-3-N-Butylphthalide consumption at the regional and country levels. It quantifies market size and growth potential for each region and its key countries, and outlines market development, outlook, addressable space, and national production.
Chapter 5: Analyzes market segments by Type, covering the size and growth potential of each segment to help readers identify “blue ocean” opportunities.
Chapter 6: Analyzes market segments by Application, covering the size and growth potential of each segment to help readers identify “blue ocean” opportunities in downstream markets.
Chapter 7: Profiles key players, detailing the fundamentals of major companies, including product production/output, value, price, gross margin, product portfolio/introductions, and recent developments.
Chapter 8: Reviews the industry value chain, including upstream and downstream segments.
Chapter 9: Discusses market dynamics and recent developments, including drivers, restraints, challenges and risks for manufacturers, U.S. Tariffs and relevant policy analysis.
Chapter 10: Summarizes the key findings and conclusions of the report.
QYRESEARCH'S STRENGTHS
Unlike generic global market reports, this study combines macro-level industry trends with hyper-local operational intelligence, empowering data-driven decisions across the Compound Chocolate value chain, addressing:
We identify regional market threats and growth prospects to guide your overseas layout.
We adjust product portfolios in line with local consumption habits.
We unpack rivals’ operation strategies for scattered and highly concentrated industries.
We cover competition landscape, full supply chain and quantified market size data, and deliver tailor-made customized surveys to meet your unique business demands.
We own self-owned massive exclusive databases, backed by 19 years of global market research experience across thousands of sectors.
Our team operates 24 hours a day, 365 days a year, enabling ultra-fast report turnaround to respond to your research needs efficiently.
We integrate regional risk assessment, localized product optimization and competitor analysis to deliver actionable market strategies.
All data is cross-verified from multiple industry sources to deliver thorough, precise analysis that supports reliable corporate strategic decisions.
We provide responsive, dedicated after-sales support to resolve all follow-up inquiries about reports, data and industry interpretation.
TABLE OF CONTENTS
1 Dl-3-N-Butylphthalide Market Overview
1.1 Product Definition
1.2 Dl-3-N-Butylphthalide by Type
1.2.1 Global Dl-3-N-Butylphthalide Market Value Growth Rate Analysis by Type: 2025 vs 2032
1.2.2 Purity≥99%
1.2.3 Purity≥99.5%
1.3 Dl-3-N-Butylphthalide by Application
1.3.1 Global Dl-3-N-Butylphthalide Market Value Growth Rate Analysis by Application: 2025 vs 2032
1.3.2 Capsule
1.3.3 Injection Solution
1.4 Global Market Growth Prospects
1.4.1 Global Dl-3-N-Butylphthalide Production Value Estimates and Forecasts (2021–2032)
1.4.2 Global Dl-3-N-Butylphthalide Production Capacity Estimates and Forecasts (2021–2032)
1.4.3 Global Dl-3-N-Butylphthalide Production Estimates and Forecasts (2021–2032)
1.4.4 Global Dl-3-N-Butylphthalide Market Average Price Estimates and Forecasts (2021–2032)
1.5 Assumptions and Limitations
2 Market Competition by Manufacturers
2.1 Global Dl-3-N-Butylphthalide Production Market Share by Manufacturers (2021–2026)
2.2 Global Dl-3-N-Butylphthalide Production Value Market Share by Manufacturers (2021–2026)
2.3 Global Key Players of Dl-3-N-Butylphthalide, Industry Ranking, 2024 vs 2025
2.4 Global Dl-3-N-Butylphthalide Market Share by Company Tier (Tier 1, Tier 2, Tier 3)
2.5 Global Dl-3-N-Butylphthalide Average Price by Manufacturers (2021–2026)
2.6 Global Key Manufacturers of Dl-3-N-Butylphthalide, Manufacturing Footprints and Headquarters
2.7 Global Key Manufacturers of Dl-3-N-Butylphthalide, Product Offerings and Applications
2.8 Global Key Manufacturers of Dl-3-N-Butylphthalide, Date of Entry into the Industry
2.9 Dl-3-N-Butylphthalide Market Competitive Situation and Trends
2.9.1 Dl-3-N-Butylphthalide Market Concentration Rate
2.9.2 Top 5 and Top 10 Global Dl-3-N-Butylphthalide Players Market Share by Revenue
2.10 Mergers & Acquisitions and Expansion
3 Dl-3-N-Butylphthalide Production by Region
3.1 Global Dl-3-N-Butylphthalide Production Value Estimates and Forecasts by Region: 2021 vs 2025 vs 2032
3.2 Global Dl-3-N-Butylphthalide Production Value by Region (2021–2032)
3.2.1 Global Dl-3-N-Butylphthalide Production Value by Region (2021–2026)
3.2.2 Global Forecasted Production Value of Dl-3-N-Butylphthalide by Region (2027–2032)
3.3 Global Dl-3-N-Butylphthalide Production Estimates and Forecasts by Region: 2021 vs 2025 vs 2032
3.4 Global Dl-3-N-Butylphthalide Production Volume by Region (2021–2032)
3.4.1 Global Dl-3-N-Butylphthalide Production by Region (2021–2026)
3.4.2 Global Forecasted Production of Dl-3-N-Butylphthalide by Region (2027–2032)
3.5 Global Dl-3-N-Butylphthalide Market Price Analysis by Region (2021–2026)
3.6 Global Dl-3-N-Butylphthalide Production, Value, and Year-over-Year Growth
3.6.1 China Dl-3-N-Butylphthalide Production Value Estimates and Forecasts (2021–2032)
4 Dl-3-N-Butylphthalide Consumption by Region
4.1 Global Dl-3-N-Butylphthalide Consumption Estimates and Forecasts by Region: 2021 vs 2025 vs 2032
4.2 Global Dl-3-N-Butylphthalide Consumption by Region (2021–2032)
4.2.1 Global Dl-3-N-Butylphthalide Consumption by Region (2021–2026)
4.2.2 Global Dl-3-N-Butylphthalide Forecasted Consumption by Region (2027–2032)
4.3 North America
4.3.1 North America Dl-3-N-Butylphthalide Consumption Growth Rate by Country: 2021 vs 2025 vs 2032
4.3.2 North America Dl-3-N-Butylphthalide Consumption by Country (2021–2032)
4.3.3 U.S.
4.3.4 Canada
4.4 Europe
4.4.1 Europe Dl-3-N-Butylphthalide Consumption Growth Rate by Country: 2021 vs 2025 vs 2032
4.4.2 Europe Dl-3-N-Butylphthalide Consumption by Country (2021–2032)
4.4.3 Germany
4.4.4 France
4.4.5 U.K.
4.4.6 Italy
4.4.7 Russia
4.5 Asia Pacific
4.5.1 Asia Pacific Dl-3-N-Butylphthalide Consumption Growth Rate by Region: 2021 vs 2025 vs 2032
4.5.2 Asia Pacific Dl-3-N-Butylphthalide Consumption by Region (2021–2032)
4.5.3 China
4.5.4 Japan
4.5.5 South Korea
4.5.6 China Taiwan
4.5.7 Southeast Asia
4.5.8 India
4.6 Latin America, Middle East & Africa
4.6.1 Latin America, Middle East & Africa Dl-3-N-Butylphthalide Consumption Growth Rate by Country: 2021 vs 2025 vs 2032
4.6.2 Latin America, Middle East & Africa Dl-3-N-Butylphthalide Consumption by Country (2021–2032)
4.6.3 Mexico
4.6.4 Brazil
4.6.5 Turkey
4.6.6 GCC Countries
5 Segment by Type
5.1 Global Dl-3-N-Butylphthalide Production by Type (2021–2032)
5.1.1 Global Dl-3-N-Butylphthalide Production by Type (2021–2026)
5.1.2 Global Dl-3-N-Butylphthalide Production by Type (2027–2032)
5.1.3 Global Dl-3-N-Butylphthalide Production Market Share by Type (2021–2032)
5.2 Global Dl-3-N-Butylphthalide Production Value by Type (2021–2032)
5.2.1 Global Dl-3-N-Butylphthalide Production Value by Type (2021–2026)
5.2.2 Global Dl-3-N-Butylphthalide Production Value by Type (2027–2032)
5.2.3 Global Dl-3-N-Butylphthalide Production Value Market Share by Type (2021–2032)
5.3 Global Dl-3-N-Butylphthalide Price by Type (2021–2032)
6 Segment by Application
6.1 Global Dl-3-N-Butylphthalide Production by Application (2021–2032)
6.1.1 Global Dl-3-N-Butylphthalide Production by Application (2021–2026)
6.1.2 Global Dl-3-N-Butylphthalide Production by Application (2027–2032)
6.1.3 Global Dl-3-N-Butylphthalide Production Market Share by Application (2021–2032)
6.2 Global Dl-3-N-Butylphthalide Production Value by Application (2021–2032)
6.2.1 Global Dl-3-N-Butylphthalide Production Value by Application (2021–2026)
6.2.2 Global Dl-3-N-Butylphthalide Production Value by Application (2027–2032)
6.2.3 Global Dl-3-N-Butylphthalide Production Value Market Share by Application (2021–2032)
6.3 Global Dl-3-N-Butylphthalide Price by Application (2021–2032)
7 Key Companies Profiled
7.1 Xianju Pharmaceutical
7.1.1 Xianju Pharmaceutical Dl-3-N-Butylphthalide Company Information
7.1.2 Xianju Pharmaceutical Dl-3-N-Butylphthalide Product Portfolio
7.1.3 Xianju Pharmaceutical Dl-3-N-Butylphthalide Production, Value, Price, and Gross Margin (2021–2026)
7.1.4 Xianju Pharmaceutical Main Business and Markets Served
7.1.5 Xianju Pharmaceutical Recent Developments/Updates
7.2 CSPC Pharmaceutical
7.2.1 CSPC Pharmaceutical Dl-3-N-Butylphthalide Company Information
7.2.2 CSPC Pharmaceutical Dl-3-N-Butylphthalide Product Portfolio
7.2.3 CSPC Pharmaceutical Dl-3-N-Butylphthalide Production, Value, Price, and Gross Margin (2021–2026)
7.2.4 CSPC Pharmaceutical Main Business and Markets Served
7.2.5 CSPC Pharmaceutical Recent Developments/Updates
8 Industry Chain and Sales Channels Analysis
8.1 Dl-3-N-Butylphthalide Industry Chain Analysis
8.2 Dl-3-N-Butylphthalide Raw Material Supply Analysis
8.2.1 Key Raw Materials
8.2.2 Raw Materials Key Suppliers
8.3 Dl-3-N-Butylphthalide Production Modes and Processes
8.4 Dl-3-N-Butylphthalide Sales and Marketing
8.4.1 Dl-3-N-Butylphthalide Sales Channels
8.4.2 Dl-3-N-Butylphthalide Distributors
8.5 Dl-3-N-Butylphthalide Customer Analysis
9 Dl-3-N-Butylphthalide Market Dynamics
9.1 Dl-3-N-Butylphthalide Industry Trends
9.2 Dl-3-N-Butylphthalide Market Drivers
9.3 Dl-3-N-Butylphthalide Market Challenges
9.4 Dl-3-N-Butylphthalide Market Restraints
9.5 Impact of U.S. Tariffs
10 Research Findings and Conclusion
11 Methodology and Data Source
11.1 Methodology/Research Approach
11.1.1 Research Programs/Design
11.1.2 Market Size Estimation
11.1.3 Market Breakdown and Data Triangulation
11.2 Data Source
11.2.1 Secondary Sources
11.2.2 Primary Sources
11.3 Author List
11.4 Disclaimer
TABLE OF FIGURES
List of Tables
List of Figures
KEY QUESTIONS ADDRESSED BY THE REPORT
Related Reports
The global Dl-3-N-Butylphthalide market is projected to grow from US$ million in 2025 to US$ million by 2032, at a CAGR of %(2026-2032), driven by critical product segments and diverse end‑use applications, while evolving U.S. tariff policies introduce trade‑cost volatility and supply‑chain uncertainty.
Published Date: 2026-03-26
Pages: 123
USD 4900.00
(Single User License)
The global Dl-3-N-Butylphthalide market size was US$ million in 2025 and is forecast to reach a readjusted size of US$ million by 2032 with a CAGR of %during the forecast period 2026-2032.
Published Date: 2026-03-26
Pages: 68
USD 4250.00
(Single User License)
The global market for Dl-3-N-Butylphthalide was estimated to be worth US$ million in 2025 and is projected to reach US$ million, growing at a CAGR of %from 2026 to 2032.
Published Date: 2026-01-09
Pages: 89
USD 3950.00
(Single User License)
The global market for Dl-3-N-Butylphthalide was estimated to be worth US$ million in 2024 and is forecast to a readjusted size of US$ million by 2031 with a CAGR of %during the forecast period 2025-2031.
Published Date: 2025-09-13
Pages: 85
USD 3950.00
(Single User License)
The global Dl-3-N-Butylphthalide market is projected to grow from US$ million in 2024 to US$ million by 2031, at a CAGR of %(2025-2031), driven by critical product segments and diverse end‑use applications, while evolving U.S. tariff policies introduce trade‑cost volatility and supply‑chain uncertainty.
Published Date: 2025-08-05
Pages: 112
USD 4900.00
(Single User License)
The global Dl-3-N-Butylphthalide market size was US$ million in 2024 and is forecast to a readjusted size of US$ million by 2031 with a CAGR of %during the forecast period 2025-2031.
Published Date: 2025-03-10
Pages: 75
USD 4250.00
(Single User License)
The global market for Dl-3-N-Butylphthalide was valued at US$ million in the year 2024 and is projected to reach a revised size of US$ million by 2031, growing at a CAGR of %during the forecast period.
Published Date: 2025-03-10
Pages: 78
USD 2900.00
(Single User License)
DL-3-n-Butylphthalide is the racemic form of (-)-butylphthalide, a phthalide that has been found in A. graveolens, that has diverse biological activities, including antiplatelet, neuroprotective, and antioxidative properties. DL-3-n-Butylphthalide inhibits ADP-, thrombin-, and arachidonic acid-induced aggregation of isolated washed human platelets when used at concentrations of 30, 100, and 300 µM, respectively. It inhibits the phosphorylation of calcium-dependent cytosolic phospholipase A2 (cPLA2) induced by ADP and reduces thromboxane A2 (TXA2) production induced by thrombin or collagen in isolated washed human platelets at concentrations ranging from 30 to 300 µM. DL-3-n-Butylphthalide also inhibits caspase-3 activation, decreases reactive oxygen species (ROS) production and JNK phosphorylation, and prevents cell death induced by serum deprivation in primary mouse cortical neurons when used at a concentration of 10 µM. It reduces infarct volume, as well as caspase-3 activation and JNK phosphorylation in the peri-infarct region, in a mouse model of right middle cerebral artery occlusion (MCAO) with bilateral common carotid artery ligation when administered at a dose of 100 mg/kg one hour following occlusion.
Published Date: 2024-08-29
Pages: 76
USD 2900.00
(Single User License)
DL-3-n-Butylphthalide is the racemic form of (-)-butylphthalide, a phthalide that has been found in A. graveolens, that has diverse biological activities, including antiplatelet, neuroprotective, and antioxidative properties. DL-3-n-Butylphthalide inhibits ADP-, thrombin-, and arachidonic acid-induced aggregation of isolated washed human platelets when used at concentrations of 30, 100, and 300 µM, respectively. It inhibits the phosphorylation of calcium-dependent cytosolic phospholipase A2 (cPLA2) induced by ADP and reduces thromboxane A2 (TXA2) production induced by thrombin or collagen in isolated washed human platelets at concentrations ranging from 30 to 300 µM. DL-3-n-Butylphthalide also inhibits caspase-3 activation, decreases reactive oxygen species (ROS) production and JNK phosphorylation, and prevents cell death induced by serum deprivation in primary mouse cortical neurons when used at a concentration of 10 µM. It reduces infarct volume, as well as caspase-3 activation and JNK phosphorylation in the peri-infarct region, in a mouse model of right middle cerebral artery occlusion (MCAO) with bilateral common carotid artery ligation when administered at a dose of 100 mg/kg one hour following occlusion.
Published Date: 2024-08-29
Pages: 94
USD 4350.00
(Single User License)
DL-3-n-Butylphthalide is the racemic form of (-)-butylphthalide, a phthalide that has been found in A. graveolens, that has diverse biological activities, including antiplatelet, neuroprotective, and antioxidative properties. DL-3-n-Butylphthalide inhibits ADP-, thrombin-, and arachidonic acid-induced aggregation of isolated washed human platelets when used at concentrations of 30, 100, and 300 µM, respectively. It inhibits the phosphorylation of calcium-dependent cytosolic phospholipase A2 (cPLA2) induced by ADP and reduces thromboxane A2 (TXA2) production induced by thrombin or collagen in isolated washed human platelets at concentrations ranging from 30 to 300 µM. DL-3-n-Butylphthalide also inhibits caspase-3 activation, decreases reactive oxygen species (ROS) production and JNK phosphorylation, and prevents cell death induced by serum deprivation in primary mouse cortical neurons when used at a concentration of 10 µM. It reduces infarct volume, as well as caspase-3 activation and JNK phosphorylation in the peri-infarct region, in a mouse model of right middle cerebral artery occlusion (MCAO) with bilateral common carotid artery ligation when administered at a dose of 100 mg/kg one hour following occlusion.
Published Date: 2024-08-29
Pages: 125
USD 4900.00
(Single User License)
The global Dl-3-N-Butylphthalide market is projected to grow from US$ million in 2025 to US$ million by 2032, at a CAGR of %(2026-2032), driven by critical product segments and diverse end‑use applications, while evolving U.S. tariff policies introduce trade‑cost volatility and supply‑chain uncertainty.
Published: 2026-03-26
Pages: 123
The global Dl-3-N-Butylphthalide market size was US$ million in 2025 and is forecast to reach a readjusted size of US$ million by 2032 with a CAGR of %during the forecast period 2026-2032.
Published: 2026-03-26
Pages: 68
The global market for Dl-3-N-Butylphthalide was estimated to be worth US$ million in 2025 and is projected to reach US$ million, growing at a CAGR of %from 2026 to 2032.
Published: 2026-01-09
Pages: 89
The global market for Dl-3-N-Butylphthalide was estimated to be worth US$ million in 2024 and is forecast to a readjusted size of US$ million by 2031 with a CAGR of %during the forecast period 2025-2031.
Published: 2025-09-13
Pages: 85
The global Dl-3-N-Butylphthalide market is projected to grow from US$ million in 2024 to US$ million by 2031, at a CAGR of %(2025-2031), driven by critical product segments and diverse end‑use applications, while evolving U.S. tariff policies introduce trade‑cost volatility and supply‑chain uncertainty.
Published: 2025-08-05
Pages: 112
The global Dl-3-N-Butylphthalide market size was US$ million in 2024 and is forecast to a readjusted size of US$ million by 2031 with a CAGR of %during the forecast period 2025-2031.
Published: 2025-03-10
Pages: 75
The global market for Dl-3-N-Butylphthalide was valued at US$ million in the year 2024 and is projected to reach a revised size of US$ million by 2031, growing at a CAGR of %during the forecast period.
Published: 2025-03-10
Pages: 78
DL-3-n-Butylphthalide is the racemic form of (-)-butylphthalide, a phthalide that has been found in A. graveolens, that has diverse biological activities, including antiplatelet, neuroprotective, and antioxidative properties. DL-3-n-Butylphthalide inhibits ADP-, thrombin-, and arachidonic acid-induced aggregation of isolated washed human platelets when used at concentrations of 30, 100, and 300 µM, respectively. It inhibits the phosphorylation of calcium-dependent cytosolic phospholipase A2 (cPLA2) induced by ADP and reduces thromboxane A2 (TXA2) production induced by thrombin or collagen in isolated washed human platelets at concentrations ranging from 30 to 300 µM. DL-3-n-Butylphthalide also inhibits caspase-3 activation, decreases reactive oxygen species (ROS) production and JNK phosphorylation, and prevents cell death induced by serum deprivation in primary mouse cortical neurons when used at a concentration of 10 µM. It reduces infarct volume, as well as caspase-3 activation and JNK phosphorylation in the peri-infarct region, in a mouse model of right middle cerebral artery occlusion (MCAO) with bilateral common carotid artery ligation when administered at a dose of 100 mg/kg one hour following occlusion.
Published: 2024-08-29
Pages: 76
DL-3-n-Butylphthalide is the racemic form of (-)-butylphthalide, a phthalide that has been found in A. graveolens, that has diverse biological activities, including antiplatelet, neuroprotective, and antioxidative properties. DL-3-n-Butylphthalide inhibits ADP-, thrombin-, and arachidonic acid-induced aggregation of isolated washed human platelets when used at concentrations of 30, 100, and 300 µM, respectively. It inhibits the phosphorylation of calcium-dependent cytosolic phospholipase A2 (cPLA2) induced by ADP and reduces thromboxane A2 (TXA2) production induced by thrombin or collagen in isolated washed human platelets at concentrations ranging from 30 to 300 µM. DL-3-n-Butylphthalide also inhibits caspase-3 activation, decreases reactive oxygen species (ROS) production and JNK phosphorylation, and prevents cell death induced by serum deprivation in primary mouse cortical neurons when used at a concentration of 10 µM. It reduces infarct volume, as well as caspase-3 activation and JNK phosphorylation in the peri-infarct region, in a mouse model of right middle cerebral artery occlusion (MCAO) with bilateral common carotid artery ligation when administered at a dose of 100 mg/kg one hour following occlusion.
Published: 2024-08-29
Pages: 94
DL-3-n-Butylphthalide is the racemic form of (-)-butylphthalide, a phthalide that has been found in A. graveolens, that has diverse biological activities, including antiplatelet, neuroprotective, and antioxidative properties. DL-3-n-Butylphthalide inhibits ADP-, thrombin-, and arachidonic acid-induced aggregation of isolated washed human platelets when used at concentrations of 30, 100, and 300 µM, respectively. It inhibits the phosphorylation of calcium-dependent cytosolic phospholipase A2 (cPLA2) induced by ADP and reduces thromboxane A2 (TXA2) production induced by thrombin or collagen in isolated washed human platelets at concentrations ranging from 30 to 300 µM. DL-3-n-Butylphthalide also inhibits caspase-3 activation, decreases reactive oxygen species (ROS) production and JNK phosphorylation, and prevents cell death induced by serum deprivation in primary mouse cortical neurons when used at a concentration of 10 µM. It reduces infarct volume, as well as caspase-3 activation and JNK phosphorylation in the peri-infarct region, in a mouse model of right middle cerebral artery occlusion (MCAO) with bilateral common carotid artery ligation when administered at a dose of 100 mg/kg one hour following occlusion.
Published: 2024-08-29
Pages: 125
REPORT COVERAGE
DESCRIPTION
OVERVIEW
MARKET SEGMENTATION
CHAPTER OUTLINE
QYRESEARCH'S STRENGTHS
TABLE OF CONTENTS
TABLE OF FIGURES
RLEATED REPORTS
INTEREST IN THIS REPORT?
Get A Free Sample
Request For Quotation
OR
NEED A CUSTOMIZED REPORT?
Customized Report
Request Sample
Pre-Order Enquiry
Add to Cart
Buy Now